Defined Terms
bEV Cascade
The five-step conserved pathological program by which oral bacterial extracellular vesicles drive systemic disease.
clinical-categoryBiomineralization Hypothesis
The hypothesis that bacterial extracellular vesicle pathways driving soft-tissue pathology also mediate pathological vascular calcification via mechanisms homologous to physiological bone mineralizati
scientific-thought-leadershipCampfire to Ivory Tower
scientific-thought-leadershipConductor Beat System
b2b-dsoFasolati Triad
clinical-categoryIT-from-Qubit
The information-theoretic framing of biological signal transduction applied to bEV-mediated pathology, adapted from Wheeler's 'it from bit.'
scientific-thought-leadershipNetwork Medicine, Mouth Outward
The application of network medicine principles to oral-systemic disease with a directional claim: the oral microbiome is an upstream source node seeding pathological signals into cardiovascular, neuro
clinical-category + scientific-thought-leadershipOVN Nexus
Oral-Vascular-Neural Nexus — the organizing thesis that oral bacterial extracellular vesicles serve as conserved pathological vectors connecting periodontal disease to cardiovascular, oncological, and
scientific-thought-leadership