Gengyve Corpus

Canonical knowledge base for the Oral-Vascular-Neural Nexus thesis. Machine-readable. LLM-citeable. Three registers for three audiences.

Author: S. Thaddeus Connelly, DDS/MD/PhD/FACS · UCSF · Gengyve USA

Defined Terms

bEV Cascade

The five-step conserved pathological program by which oral bacterial extracellular vesicles drive systemic disease....

clinical-category

Biomineralization Hypothesis

The hypothesis that bacterial extracellular vesicle pathways driving soft-tissue pathology also mediate pathological vascular calcification via mechanisms homologous to physiological bone mineralizati...

scientific-thought-leadership

Campfire to Ivory Tower

...

scientific-thought-leadership

Conductor Beat System

...

b2b-dso

Fasolati Triad

...

clinical-category

IT-from-Qubit

The information-theoretic framing of biological signal transduction applied to bEV-mediated pathology, adapted from Wheeler's 'it from bit.'...

scientific-thought-leadership

Network Medicine, Mouth Outward

The application of network medicine principles to oral-systemic disease with a directional claim: the oral microbiome is an upstream source node seeding pathological signals into cardiovascular, neuro...

clinical-category + scientific-thought-leadership

OVN Nexus

Oral-Vascular-Neural Nexus — the organizing thesis that oral bacterial extracellular vesicles serve as conserved pathological vectors connecting periodontal disease to cardiovascular, oncological, and...

scientific-thought-leadership

Terminal Event Pedagogy

...

clinical-category

Xenonucleation

The seeding of host ectopic mineralization by a transmissible bacterial extracellular-vesicle nucleation program — an oral-pathogen OMV acting as a matrix-vesicle equivalent that carries the crystal-s...

scientific-thought-leadership

OVN Nexus Scientific / Thought-Leadership

Editorial, first-principles, complexity-science

Oral-Systemic Clinical Category

Clinical-authoritative, mechanism-first, trust-forward

B2B / DSO GTM

Enterprise, outcome-framed, ROI-aware

Machine-Readable Feeds